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I am eighty years old and suffer from AF (Atrial Fibrillation) and was advised to take 2.5 mg Apixaban twice a day. Antibiotics such as clarithromycin may also increase the risk of side effects associated with Eliquis.īottom line: be vigilant for signs of bleeding and always check about drug interactions before adding an herb, an OTC drug or another prescription medication to Eliquis.Antifungal medications ( ketoconazole and itraconazole) may increase the risk of toxicity and bleeding.Antiseizure drugs such as carbamazepine and phenytoin may reduce the effective of Eliquis.Other anticoagulants such as clopidogrel or warfarin may increase bleeding risk when combined with Eliquis.NSAIDs (all anti-inflammatory drugs including ibuprofen, naproxen, diclofenac, etc) could increase the risk of bleeding).Aspirin (may increase the risk of bleeding while taking Eliquis).Swelling of tongue or face or trouble breathing also requires emergency treatment.ĭo not take any other drugs without checking first with your prescriber.

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Skin Rash could signal a serious allergic reaction.Report such a side effect promptly to the prescriber Swelling of the joints or joint pain could signal bleeding in that area.A bad headache or a feeling of dizziness should also be discussed immediately as these could be signs of bleeding in the brain. Let your doctor know if your gums bleed after brushing or flossing your teeth or if you experience nosebleeds or pink, red or brown urine.If you throw up and detect blood or anything that looks vaguely like coffee grounds, that would be a sign that there might be bleeding in the stomach. Dark or tarry stools would be a possible warning sign of digestive tract bleeding. Notify your doctor promptly if this occurs. Patients can bruise or bleed more easily when on this drug. The most serious complication is bleeding.ELIQUIS (APIXABAN) SIDE EFFECTS & INTERACTIONS: The drug should never be stopped suddenly. Many patients may do quite well on Eliquis, but we would hope that a knowledgeable cardiologist would be involved in such a decision and provide adequate oversight. There is no “antidote” to an overdose that might lead to hemorrhage. He also pointed out that it is hard to reverse the anticoagulant effect. Unlike with warfarin, there is no easy blood test to tell when you have achieved the optimal blood thinning effect. He is cautious about the new medications because he says it is hard to assess their effectiveness in any given patient. We have consulted a cardiologist at the Cleveland Clinic who deals with atrial fibrillation (AFib) on a regular basis. I am looking for more information on Eliquis to evaluate the pros and cons. I have been taking Coumadin (warfarin) for years, however, my doctor recently recommended that I switch to Xarelto or Eliquis.












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